Purina scientists have found a way to safely reduce active levels of the major cat allergen found in cats’ saliva. This is a significant breakthrough as it can transform the way people manage cat allergens. Now, rather than limiting their exposure to the cat, individuals can limit their exposure to the allergen instead.




Dr. Ebenezer Satyaraj

Purina Immunologist

Dr. Satyaraj is the lead Purina investigator on the research for cat allergens.

quoting These allergens have created a huge barrier to cat ownership and may limit the loving interactions between cat lovers and cats.

Dr. Ebenezer Satyaraj

Impact of Cat Allergens

Many people go to great lengths to reduce allergens in their environment, such as daily cleaning and frequent washing. Cat allergens can limit people’s interactions with cats, and sadly, they’re also a common reason why cats are given to shelters. Due to this, allergens can create an additional barrier to cat adoption and ownership.


As many as 1 in 5 adults worldwide experience cat allergens.


Avoidance or rehoming is a common recommendation to manage cat allergens.


What are Cat Allergens?

Although many people believe cat allergens stem from the cat’s hair or dander, the major cat allergen is Fel d 1. This protein is found primarily in the cat’s saliva. Fel d 1 is then transferred to the cat’s hair and skin during grooming. As the cat sheds, the allergen on the hair and dander is dispersed throughout the home.

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What about Hypoallergenic Cats?

Contrary to popular belief, there are no truly hypoallergenic cats. All cats—even hairless ones—produce Fel d 1, regardless of breed, age, sex or neuter status. Additionally, Fel d 1 levels are not affected by hair color or length.

Fel d 1: The Major Cat Allergen

[Fel • Dee • One] noun

This is a protein produced in a cat’s salivary and sebaceous (skin) glands. It gets transferred to cat’s hair and skin during grooming then is dispersed in the environment via hair and dander (dried flakes of skin).


A Revolutionary, Feline-Friendly Way to Manage Cat Allergens

After more than a decade of research, Purina scientists discovered the primary cat allergen can be reduced when cats eat a diet containing an egg product ingredient with antibodies. These antibodies safely bind and block Fel d 1 in cats’ saliva and this inactive Fel d 1 gets transferred to the hair when grooming. This is a safe, feline-friendly approach and does not interfere with with Fel d 1 production or change the cats’ overall physiology.


According to a Landmark Purina Study

Of cats fed this egg ingredient, 97% showed decreased levels of active Fel d 1 on their hair and dander. On average, there was a 47% reduction of active Fel d 1 on cats’ hair beginning with the third week of feeding the diet.


The decrease in active Fel d 1 on cats’ hair and dander can help reduce cat allergens that get shed into the environment.

quoting Our discovery has the potential to transform how people manage cat allergens.

-Dr. Ebenezer Satyaraj.